The interior wiring harness will depend more on the options you have in your vehicle than on the engine it boasts, so not issues there.
However, LTD was right in the fact that you will require everything under the hood/truck. From the exhaust "Y" all the way to the front.
You should have a 45rfe which is the same as the 4.7L. However the Hemi runs on the 545rfe which is very similar. In fact some people have actually "upgraded" their 45rfe to a 545rfe with a simple TCM swap and flash.
As I have told others, I believe the easiest and cheapest way of getting this done is to have a donor truck you can park right besides yours and then the parts store is sitting a few feet away from where you need it... A good donor could be a truck that was totaled in a crash, but the mechanical is still good. Avoid fires, as all the needed harnesses are unusable which is the most important part for you.
So basically, it will be easier and cheaper to look for a good deal on a trade and put a little TLC on a complete truck that might need a few repairs rather than trying to achieve this swap, unless you have access to a very low cost donor, lots of comfortable space to work in, the time and desire to do this kinda work.
Hope this helps.