My HMMWV tires were way off-balance. They have the run-flat inserts. 37x12.5x16, things weigh like 165 lbs each.
Experts said they couldn't be balanced, so I bought some Centramatics
http://www.centramatic.com/
They made a difference, but a friend of mine who runs an off-road custom shop (Adrenaline Off Road) who had bought a HMMWV after seeing mine, said that was nonsense.
He has a balancing/ROAD FORCE (I forget the make/model, but he said it was around $18,000 installed) machine he had done my Tacoma tires on, and my daughter's Matrix tires (we installed/balanced), so I said what the heck, let's try.
EZPZ, no problem at all. Tires balanced GREAT. In the process we noted two rims are "tweaked" such that the midline of the respective tires "wobbles" about 1/2 inch. Will deal with that later.
Might need another machine, location that deals with larger tires.
Always listen to the experts. They'll tell you what's impossible, then you go out and do it. (Robert Heinlein, paraphrased).