redline si-1 thread
So the industry theory is all you need is top tier, and somehow that is better then lower detergent fuels. The good news, it doesn't take a Harvard education to solve this. All you need is a cheap boroscopes, guys like hemi395 have posted pics on the board, and the ability to remove a spark plug. This is something a few of us explored back in the day, and of everything I have found the only proven treatment is redline si-1 and more importantly it has to be a concentrated dose. Now, in theory you can also use other fuel treatments, but it would have to be multiple bottles at once, no doubt concentration level matters. Go figure since that is the theory on top tier, they say more is better, but your question really is how much is best, and only you can answer that by sticking a scope down the hole.
There are other treatments that show promise such as sea foam, but that needs to go through vac lines to accomplish something si-1 does added to gas, plus doesn't do anything for injectors. So other considerations is the process of cleaning versus product. Sea foam is nothing special, no known good cleaning products, but because of process it can be as good as anything. Back in the day guys even used water, not in fuel, but right into combustion chamber for a soak.
If you use si-1 the best time to do this is a tank before an oil change. The info in the thread suggests it is best used only this time and not as a maintenance dose, with proof. How often? If you have a boroscopes easy to set an interval.