I have a 2017 Laramie and I have the white courtesy light (puddle)/sequential amber turn combo led strips just under the doors on each side. They come on white when the interior courtesy lights come on (unlock, dooe open, etc) and work with the turns/flasher sequentially in amber.
I ran the courtesy/pubbe light wires (in wire looms) under the cab and into the rear floor bins thorugh the rubber grommet there....sealed everything underneath with silicone. Then ran the wires up under the carpet to the plugs behind the rear seats that have the pin for the small led lights under the seat bottoms. Should be a similar set up in your truck to use the plug for those interior leds. Turn signal wires ran in looms to the rear turn signals.
When to have them come on is your choice...what color are they? If acting as running lights you could have tthem on with the lights...if they are white, then you need to wire them with the courtesy lights when doors open/unlock.