Not really - the 8 speed transmission ensures the wheel torque required will be delivered. Moving to a 4.10 rear - simply shifts you up one gear. You are still at some ungodly RPM trying to pull a trailer up hills or travel trailers with a huge coefficient of drag. The engine torque is only about 270ft/lbs which is rather weak for most towing. The lower gears help you get going in first gear, but that is about it. It does, take the torque load off the transmission, but at the expense of higher RPM. Gears are definitely good for low speed use - bogging through mud, pulling out tree stumps, etc. Towing with the Pentastar V6 at regular highway speeds is a different thing. You are trying to just maintain speed when you encounter a hill. It really does not do well in my real world experience with a 4500lb 22ft Micro Minnnie. It spends a LOT of time at high RPM trying to make use of the peak torque that happens a little over 4k RPM.
I have poured over the math and lived the practical reality - in the end, I am putting a supercharger on my V6 for pulling because I need the extra 100ft/lbs of torque.
https://www.ramforum.com/threads/2015-pentastar-v6-towing.171807/page-6#post-2438098
You can do some visual work with how gear changes will impact your total ratio to the ground. The 8 speed trans is already so good at getting the engine to its sweet spot - gears don't help highway driving.
https://www.blocklayer.com/rpm-gear.aspx