You may be good on stock internals? I've known a good number of people who've added a power adder to their GM LS3's making 700+ HP on stock internals and they were fine, but I'm not that familiar with the quality of stock internals on our HEMIs.
Me personally, I'd probably start with a good foundation... i.e. intake, long tube headers, a cam thats going to work well with the power adder, suspension system mods, braking system mods, etc. etc. Basically all the little things. No sense to me putting a power adder on when what matters the most is being able to put that power down! And stopping!