Cylinder 1 misfire

[JW-IN-OK]

I've seen some other posts about cylinder misfires but didn't really see anything that helped for where I'm at with mine now. So I had a flashing CEL and when they pulled the code it was for a cylinder 1 misfire. I thought the best thing to do was swap spark plugs and replace the coil pack for that cylinder. I've done that and to no avail. I still get the flashing CEL on acceleration. I should note that when accelerating, I can hear a clatter, I just assumed it was the misfiring, but now I'm wondering if I've got more problems internally. It's a 6.4 Hemi in a 2014 Ram 2500 with about 175,000 miles. Thanks in advance for any advice you may have!

JW

 

[Burla]

The usual suspect is cam lob is wiped on 1, especially if you still get 1 on code after swapping plugs and coils. If your lucky it would be injectors, but it doesnt sound like this is the case.

 

[Redfisher1974]

I always swap coil and plug to another cylinder and see if code follows. But if you went new that works too

 

[Jstovall23]

What ended up happening with your issue? I have a 2015 with the 6.4l, noticed the clatter, and then noticed it was only doing it with MDS engaged. I disabled MdS and no clatter. A day later got the flashing check engine light, PO301 code for cylinder 1 misfire, truck shut down, and motor won’t turn. Waiting on a quote to replace motor. Truck has 108k miles.