Need Help! 2014 2500 6.4l V8 Throwing Codes

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CenCal Ram2500

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6.4L V8
Need some help. Bought a ram 2500 from a family friend (the original owner) 8 months ago after her husband passed.

Around 2 months ago, got the Red Lightning Bolt (Service Electronic Throttle Control). When a diagnostic was ran, P2181 – Cooling System Performance came up. Mechanic replaced the Thermostat. CEC light came back on within a day. Same Code. Took back in, mechanic said there was air bubbles in radiator line, he flushed the air bubbles. 1 week later, CEC light came back on. Codes read P3449 – Cylinder 7 Deactivation Control Circuit, and P3441 – Cylinder 6 Deactivation Control Circuit. Took to mechanic, he put a wiring harness on order, but told me I was good to drive it around in the meantime. Since then (wiring harness not installed yet), codes P04D1 – EGR, P0128 – Low Coolant Temp, P040B – EGR Temp, and P219A – Bank 1 Air/Fuel Ratio Imbalance have came up.

Any thoughts? Through personal research, I have read that voltage/short issues can cause a couple of the codes. Does this sound plausible? Has anyone had an experience with anything similar?

2014 Ram 2500
Laramie Power Wagon
V8, HEMI, 6.4 Liter
Automatic, 6-Spd, 4WD
170,000 Miles
 
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CenCal Ram2500

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P04D1 – EGR

P0128 – Low Coolant Temp

P3449 – Cylinder 7 Deactivation Control Circuit

P3441 – Cylinder 6 Deactivation Control Circuit

P040B – EGR Temp

P219A – Bank 1 Air/Fuel Ratio Imbalance

PREVIOUSLY

P2181 – Cooling System Performance
 
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CenCal Ram2500

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Update: Reflashed/Reprogrammed the PCM. Now codes read:

P2181 – Cooling System Performance
P3441 – Cylinder 6 Deactivation Control Circuit
P2311 – Ignition Coil 4 Secondary Circuit - Insufficient Ionziation

Bad PCM? Short/Ground issue? We are lost - Any thoughts on this would be greatly appreciated!
 

Daw14

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Have your battery load tested , will throw codes sometimes when they are going dead.
 

Dodge 1500 4X4

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X2 on have battery load tested, one better how old is the battery? you're this deep into it, I would have thought replacing the battery should have been your first option, I would replace your Parts cannon mechanic.
 

mjf84

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Ever figure it out? I’m having same issues
 

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