Yes you can, There are only a couple of pre-built boxes out for the 5th gens so far so they are a little pricey. Some of them require a rear seat lift to allow it to fit. You will have to buy an adapter to pull your speaker signals (L/R) and turn them into the right adapter for your amp (The red and White RF) You will also need 25 feet of 8 gauge red wire, a fuse holder (I did 80 AMP), about 12 feet of 16 gauge speaker wire and some clip on terminal connectors. I ran my Main power (The 8 Gauge) from the battery through the firewall at a rubber boot and then under the trim panels on the drivers side floor to the back of the cab. The speaker wire was connected to the existing speaker wires at the B pillars (Twisted wires in the harness, color code on this forum somewhere) and ran them back to the back of cab on each side and tied them into the adapter. The only problem is the Active Noise Cancelling System they have in these trucks. Its fed to the rear speakers and will make your subs go nuts if you go this route. I was able to tune it out mostly by settings on the amp and adapter but it is a nuisance. My subs are also currently taking up 2 of the 3 rear seats because i havent sprung on the under seat box yet. But running 2 12" subs in a ported box with a 2000 watt amp and 3 Farad Capacitor is so pleasing. I dont regret it yet. Once i buy the under seat box i will just move all my equipment to it and toss my old box. You could try to pull your signals from the front speakers instead (Ive heard the noise cancelling is only connected to the rear speakers) you would just need to add extra length to the speaker wire.
