I had a 2013 Longhorn 4x4, 5.7, 8 sp, 3:21, with soft tonneau cover and it averaged 19.5 hwy unless fighting a strong wind. Drove it 5 years, 265,000 miles, cleaned the gas carbon once last summer, due to it was avg 18. Instantly back to 19.5. 21 once with a good tail wind.
All stock, no alterations, except hard splash guards.
Just traded in Feb, 2019 Longhorn with 14,000 miles, same 5.7, 8 sp, 3:21, bed cover, the best so far is 18.4 hwy. This truck does set higher with off road pkg and air suspension.
So far its avg is 16.5 hwy, 14 local driving. I do a lot of interstate driving.
The MDS doesn't come on a much with this truck as my 2013. No ethanol did bump me from 16.5 to 18.4 last week, hand calculated. The truck display is usually high, but I have found it to be low a few times on my 2013 Ram.
Someone commented on air pressure 2-3 over suggested, and that has worked well for me also.
driving styles do matter.
The 2013 did much better if I kept it at 70 mph, vs 75 mph on interstate. On two lane hwy, it would usually get 20.
My 2019 doesn't seem to matter, it just likes the gas.
I'm going to stay on No ethanol(if posted on the pumps) to see if that is the difference. someone commented they sneak in ethanol and dont post it, it can be true, some states dont post ethanol on the pumps, such as Missouri. Iowa does post it, being a large revenue of ethanol.
I will add, the 2013 ram loved E30 gas, still got the same avg 19.5. Blender pumps are becoming more common in the midwest. Ran ethanol all 265,000 miles in the 2013 Ram.