I have a 2017 Ram 3500 Dually long bed, purchased new in 2018! I have 217,500 miles of hauling 5th wheel and bumper pull campers across the United States, so I believe I qualify on giving advice on this subject! My truck of course has the Cummins and 3.73 gearing with automatic transmission 68RFE. My truck has been serviced regularly by myself and Stealer and still OEM Emissions. If you haven't purchased yet, go with 3.73's that would be the ideal gear ration for around town and enough grunt (torque) to climb any Mtn. pass that you may travel. Flat-ground towing I have averaged 11-13mpg under good conditions, Mountainous areas and windy conditions I have seen 7-9mph. I could have bettered my mileage by backing off and slowing down, but miles meant $$$. There was not one time that I needed any more power and was very pleased with3.73's. My prior truck was a New GMC Sierra 1/2 ton with 3.03 gearing and I used as everyday truck, often pulling a 18ft bass boat, occasionally pully a motorcycle trailer with 2 Touring bikes IE Goldwing, Harley Ultra Classic but the truck was gutless, I changed out the gearing to 4.10's which made towing exceptional but fuel mpg went down, I should have went with 3.73 and would have been happy. As far as having the Cummins turning 3.73's in 3500, my opinion is the best route. Now as far as 4 wheels VS 6 wheels the difference is Day and Night. 4 Wheels pros Better Ride, 4 tires to replace, balance and rotate, 4 brakes to service, easier to park, storage box on both sides external fuel tank are available as are a larger OEM tank may be available. 4 wheel cons, less stable in Rain, Sleet, Snow, Wind, Snow Packed roads, less stopping distance VS 6 wheels. 6 Wheeled pro's , better stopping, more stable (Less lean). Any questions or comments? Post them as i'm sure there are many things I missed.