Here’s the basics. You can for sure keep your 4x4, not an issue. How much power are you wanting for your new engine? Is your old engine good right now? It’s an option to just stroke your current engine to 6.1 or 6.4 as I did. If you are set on the 6.1 srt swap, better start looking for an engine to get an idea on prices. They are getting rare and expensive.
I again highly suggest dealing with the 03-05 pcm swap first thing. If you are lucky and find a used pcm on eBay or a junkyard for about $100, buy two more oxygen sensors and some wire. By far the best thing you can do to tune your new motor. If not, you might get into a tuning nightmare that’s simply not worth the time and money. LISTEN to redtruck! I know he fought that thing for years trying every trick in the book to keep his running. He’s living the good life now haha
http://www.hemitruckclub.com/forums/f171/instructions-for-03-to-05-pcm-swap-24081.html
As far as transmissions, if you want to swap from the 545rfe, the cheapest option is a built 46re out of a 96-01 ram 1500. You need the 4x4 version, and unless you want to spend an extra $1000 on a stand-alone controller for it, you will need to change to a manual-automatic valve body, requiring you to manually shift every gear.
http://www.hemitruckclub.com/forums/f120/a518-46rh-46re-47-48re-rebuild-17576-52.html
This thread is a gold mine of info on the trans swap. The 4x4 info starts around page 52. But if you are serious about this, I would suggest starting at the beginning and reading through. Trust me, I know it’s long, I’ve read through it myself 3 times lol. This is the route I am going with my 03 4x4 this summer. Lots of guys can attest to the 545rfe being a hunk of expensive crap that’s not worth fighting.