I believe MP3 highest bitrate setting is 320 kbps. FLAC can do 1411 kbps, but typically they run about 900 kbps.
You can tell the difference if you listen to them side-by-side and know what to listen for. The easiest way to tell that mp3 is deficient compared to FLAC is when listening to long, sustained cymbal strikes. There really aren't any in "Nothing Else Matters", but if you listen for cymbals in FLAC and MP3 music you can tell the difference. Speed heavy metal like Metallica is not the best genre to test for differences in these two formats.
A really good acid test is to try "Listen to the Music" by the Doobie Brothers and focus on the cymbals, especially those with long, sustained cymbal sounds. There are several long duration cymbal strikes in this song with one at about the 9 second mark that is a good example. If you listen to it in mp3 the cymbal seems to spatter and sizzle and then dies out quickly while the CD version has a crystal clear ring to it and goes on for several seconds. I presume the FLAC version will sound similar to the CD version.
Another good test is sustained high piano notes.
May be. Or not. Sometimes remastered CD's are mixed to sound louder at the expense of wider dynamic range.
No doubt.