Completely forget about the spacer. They are just paperweights and do nothing.
Now when it comes to throttle bodies don’t just look up the biggest size you can and slap it on that’s not how they work.
The best throttle body you can get for our 5.7 would be the fastman true bore throttle body.
The throttle body is just a supporting mod though. You need a custom tune, intake, headers, exhaust, etc before you will see any real gains from the TB.
If you have the money to spend, I’d look into a list like this for real performance gains:
-ARH longtube headers
-S&B cold air intake or Vararam intake if you don’t live in a snow area.
-Exhaust (Carven progressive or Borla ProXS are the 2 biggest hits here)
-Unlocked PCM with tuner and custom tune from Hemifever or Jay Greene
-Camshaft upgrade and non MDS lifters
That’s just a start, let us help you spend your money as required