What size tire, and since alot of guys rub with the 20x9's and a 305 I'd assume you would too depending on the BS and offset combo. I am assuming you also mean negative offset and the one place you may get the most rubbing or contact is at the inner fender at firewall, fender lip where it crowns and at the bumper lip at the front. all depends on tire size too.
I have somewhere around a 3-5 drop with stock R/T wheels and I am damn close to contacting the fender lip where it crowns if I was 1/2" out farther with my offset I would be creating all sorts of body damage