Keep your rate of acceleration, slow. When climbing hills, losing top speed is preferably to mechanical issues down the line. Good Trailer hitch anti-sway bar helps a ton. If the trailer tongue weight, along with all the other weight inside your truck, puts the truck on its axle "Stops", add variable rate springs, or if money is tight, airbags.
Do not overheat your disc brakes, you will notice a grabbing-studdering, when you brake , if they are getting hot. If that happens, just stop, wherever you are, and let them cool down.
Trailer brakes are essential, anytime you are getting close to max towing and, just plain nice, at all times. Make sure the trailer brakes are functioning and add some positive trailer braking, from the cab with your brake control, if you think you may be working the trucks brakes, just a bit too much.
If you notice your rear end swaying, when passing or being passed by semi trucks or due to winds, stop and adjust the weight, in the trailer, to remove some tongue weight.
If excessive truck rear end sway continues, turn around and head home, not worth your life.
Bottom line, you need to feel you, and you truck, are in control of the weight, at all times. If not, stop, adjust or return to home. At any time, if you feel it is not safe to continue on, stop, drop the trailer and find another means to get it.
Pulling the weight is not the thing, controlling it and stopping it, when you want it, is most important.
If you have no experience towing, I do not recommend starting out at anything over 50% of MAX limits. Like with anything , new, start out small and work your way up.
Dave
