Every vehicle is going to have it's own issues. And every person is going to have their bias.
I could sit here and tell you how much I love the 1994-2001 Dodge Rams and that I think they are the greatest truck ever made, but I will spare you. I am on my third 2nd gen Ram, 2 gassers and one diesel. I will say that if you go diesel, you will not regret it. The power from a 5.9 is quite impressive. The sounds is amazing, and the fuel economy isn't too bad either. It just all depends on your taste. If you go used, and find a truck that's been maintained well, then you shouldn't have too many issues, however stuff does start to wear out. There is a negative stigma about the auto transmissions in these trucks, but many people have gotten over 200k miles on theirs without touching them. I have personally always like the interior on dodges better than any other truck. I'm not a huge fan of the 2003 or newer rams, but that's just me. I think front ends have been the biggest issue I have had with my rams, but every single one I have had has had a lift with at least 35" tires on them, so front ends don't last quite as long in that setup. I also have never bought a new vehicle and I don't think I ever will.