i have had all pioneer, alpine, kenwood in their touch screen units. i personally liked the UI of the kenwood the best.
what i would recommend is go to like a best buy where they carry all 3 brands. play with them and see what one you prefer. you have a "generous" budget so it should get you a nice radio
now keep in mind that you will get some better sound, but not the greatest. realize that when you are shopping what you see them advertise for power is max power. a radio will never use its max power. look at the rms rating of the decks. if its like it ws back in the day alpine used to have the highest rms rating (it been a long time since i sold them)