Well, let's see ....sounds like you have multiple things going on.
Let's start with the 'knocking' sound: chances are very good that one of the actuators has a cracked gear/shaft. The female portion of the drive motor has a nylon gear that fits over a square drive (door shaft). This long, female portion that rotates the door shaft commonly cracks (lengthwise) and then opens when the door reaches it's end-travel (at the most torque) and then 'skips' instead of stopping the motor. The motor keeps skipping on the shaft because there isn't enough resistance to stop it. The quick fix is to buy at least one new motor and replace it. You can ID which one it is by feeling it and you'll feel it click as it skips. If its the defrost it should be easy to get to as far as I remember. Just google a drawing of the HVAC box. All the actuators should be the same. Ebay is a cheap place to get one. Hopefully your truck doesn't have automatic (dual) temperature control. Even if it does, with luck, the motor in the back of the HVAC box isn't the problem.
As for the outside air/recirc air blend door, if it's like the HVAC boxes I've looked at, what I would do is take a strong flashlight and look 'up' from the passenger's side footwell. It's an awkward position, but on the ones I've dug into, I was able to look up through the grate to see what's going on with the blend door. It wouldn't be uncommon if the door is separating at the hinge. The hinge may not be a true hinge, more like thin piece of the plastic door which flexes open/close until after enough cycles the plastic breaks half-way. Then the door hangs down and to the side and neither opens or closes all the way. The motor will cycle until it tears the hinge the rest of the way (then the door will drop down). The quick fix I've done is to take a piece of stiff wire the right length with sharp ends (sharp like a finishing nail) and wedge the wire in there to hold the door shut until you can get at it. The actuator could be bad too. You won't have outside air, but you'll also have good heat again until you get at it (or just leave it).
Good luck.