For my work, I have had four Rams 1500's since 2015.
A 2015 Hemi with 3.92 2x4
A 2017 v6 with 3.21 2x4
An all new 2019 hemi with 3.92 2x4
A 2020 classic hemi with 3.92 2x4
I tow almost everyday. I tow an assortment of trailers; box, utility, boats, car dolly ext...
If you tow a lot a hemi with a tow gear is hands down an easy choice. You won't have to think about "can I tow this?" The hemi is capable and never complains and very stable on the highway.
My v6 Ram was a good truck and surprised me on more than one occasion. But I did ask myself often "can I tow this?" I found gas mileage is better with similar trailers maybe only 2-3mpg though. But I towed a mix of in town and highway. The v6 didn't feel as confident down the highway as the v8 but wasn't bad. It's a lighter truck. Also, my v6 wasn't a 4x4. I imagine the 4x4 v6 would have a better highway towing feel than the 2x4 model. Best of luck.