Here is what the reply was when asked what it supports and such.
Currently, we do not support the ecodiesel or the 6.4 HD models. We are working with the ecodiesel as we speak to try to make tuning for this application, but we currently do not have a scheduled release date. The 3842 or 3841 (California) will support the Hemi trucks from 2013 back to 2004 and back as far as 1999 on the other v8 engine applications for the trucks. This device will also work on the 1999 to 2012 Dodge Diesel 2500 and 3500 trucks as well with either the 5.9 Cummins or the 6.7 Cummins.
"The trans tuning is included in each power level, but yes, the tuner should work on the 8 speed transmission."