This has received a lot of interest here, Red Line SI-1...
^Keep in mind that link is the price to (2) 15oz bottles, each good for 20 gallons of gas.
Also, when shopping for Top Tier gas, AAA rated Shell the #1 for additives, I *think* Exxon was number 2. If you Google you might search to AAA top ten for additives, then check that list against your area.
I only have Sunoco by me. At 108,000 miles I just added 2 bottles of the SI-1 then filled the tank with 89 octane Top Tier.
I can offer no science or gauges but I swear the idle is noticeably smoother and the gas pedal in more responsive. I'm about 1/3 down from full with this mixture.
Many folks recommend doing this kind of "cleaning" the full tank right before an oil change. Some of the additive will find it's way into the oil. Run the gas tank near empty, fill it back up with your best gas, then do an oil/filter change.
If you are that interested, and it seems like you are, keep posting what you're doing and any results you see as you go. We all add to the library of experience here.