For quiet I have a Lexus, I don't expect my pickups to be coffin quiet. The only way to make them quieter would be to do what Lexus and Rolls do, extensive sound deadening material in the Cabs, and MUCH better door seals that completely mate the door to the cab.
My Lexus, if you just lightly sit the door closed against the door latch and the seal, each door has a motor that brings it fully closed. Poor door seal/weather stripping is probably the leading cause of sound intrusion on north American vehicles. On my wife's Jeep and my pickup, dust gets past the door seals. NONE gets past on the Lexus.
If you want to verify, take some foam and wedge it between the door and cab all the way around the rear doors, especially along the rear and bottom edge. My bet is your passenger side noise disappears. Then just figure out how to make that seal a permanent thing. Then add isolation pucks under all interior mounts.
I will say my 2021 2500 Laramie, is quieter than the 1996 2500 V10 I have, both with Duratrac tires on them.